ʻO Sesamol

ʻO Sesamol ka lehu Kaʻike Base

inoa	ʻO ka pauma Sesamol
Hoʻolaha	ʻO ka pauma
Cas	533-31-3
ʻAna	≥99%
Palekana	nsoluble i loko o ka wai a i wai wai paha, hoʻoheheʻe maoli i ka waikawa Acetic, ethyl ester.
Papale ʻaʻa	138.12 g / mole
ʻO ka Melt Point	62 a 65 ° C (144 a 149 ° F; 335 a 338 K)
Ka Lā Molecular	C7H6O3
ʻO ka paila	21 a 127 ° C (250 a 261 ° F; 394 a 400 K) i ka 5
SMILES	mmHgO1c2ccc (O) cc2OC1

He aha ka sesamol?

Ua hoʻokaʻawale ʻia ʻo Sesamol, a me nā mea hoʻokūkū pila, i nā ʻāpana kino e like me ke ake, ka lolo, nā ʻōpū a me nā keiki hoʻi.

Ke hoʻoheʻe ʻia ʻo Sesamol i loko o ke kino, pale i ka DNA ma nā pōʻino a hoʻonui i ka hoʻoponopono DNA e hoʻoponopono i ka pōʻino o hope-radiation.

Ma muli o kona ʻano vivo bioactivities, hana nui ka sesamol i ka mālama ʻana i nā maʻi like ʻole. Ua hoʻopaʻa ʻia kekahi noiʻi i ka sesamol i pale i ka hoʻokumu ʻia o nā koloni cell HepG2. Kākoʻo kēia i nā haʻawina ʻē aʻe e hōʻike ana e hōʻino ana ʻo Sesamol pauka (533-31-3) i ka hiki o nā puʻuwai o ke kanesa.

Ma ka maʻamau, ʻo ka hapa nui o nā maʻi kanesa e pono ai ka ʻoi aku o ka maʻi oxidative e like me ke kūpaʻa ʻana i nā sela olakino e mālama ai ka kaulike proliferation-apoptosis.

Ua hōʻike kekahi mau noiʻi e pili ana ka pilina o ka sesamol a me ka DNA ma ka puʻuwai o kēia hope. Ke hoʻomau nei kēlā, kahi noiʻi noiʻi hou e hōʻike ana i ke koʻina polu i hoʻoili ʻia e ka sesamol hopu i ka hanana S, a loaʻa kēia i kahi ʻano hilinaʻi. ʻO kēia ke kumu e hōʻino ai i ka sesamol i ka hōʻino o ka DNA a ke pale i ka hoʻopili ʻana o ka DNA.

ʻEkolu mau lāʻau synta o nā sesamole

1.Extraction mai Sesame aila

ʻO ka syntam Sesamol mai ka Sesame oil ka maʻalahi o nā ala ʻekolu. Eia nō naʻe, he kumu kūʻai nui. No laila ʻaʻole kūpono kēia ʻano kumu no ka hana ʻoihana ʻenehana, ʻoiai ma muli o nā kumukūʻai kiʻekiʻe.

2.Synthetic synthes mai ka piperamine

ʻOiai kūpono ia no ka hana nui no ka hana Sesamol, ʻo ke ala holoʻokoʻa no ka syntam sesamol mai ka piperamine e pili ana i ka hana liʻiliʻi ma ka wā e hana ʻia ana ke kaʻina hydrolysis a me ka hoʻoliʻiliʻi hydrolysis. Me kēia mau ʻano, hiki i ka hoʻālaʻa puaʻa ma ke ʻano he hoʻopili a me nā ʻaoʻao ʻaoʻao i ʻole e hiki ʻole ʻia.

3.Sute-synthetic alanui e hele mai ana mai jasmonaldehyde

ʻO ke ala Semi-synthetic mai ka jasmonaldehyde ka mea i hoʻohana nui ʻia ka sesame phenol synthesis synthehish e like me ka manaʻo o nā kumu waiwai. ʻO ke kaʻina e pili ai i ka maʻi hoʻoliihua a me ka hydrolysis a ma muli o kēlā, ke kūmole hōʻailona sesame he mea kiʻekiʻe a ʻoi ke kala maikaʻi.

Ke hoʻohana nei ke kaʻina hana no ka hoʻoulu ʻia ʻana o ka momona oxidant a me ka hoʻoneʻe hou aku i ka ʻenehana, e hiki ai i ka hoʻokaʻawale wikiwiki o ka huahana mai ka waho o ke kahe. Hoʻololi kēia i ka hiki o ka hopena o ka hopena i ka hanana nui. ʻAʻole he mea kupanaha ka huahana hope loa (ke kele ʻana-like-keokeo) o ke ʻano kiʻekiʻe o nā kumu a me ke kūpaʻa sesamol.

Tnā hopena koʻikoʻi o ka sesamol

Hoʻopilikia i nā hopena anti-oxidation

ʻO ka lilo ʻana i nā meaʻai kūlohelohe me nā waiwai Antioxidant maikaʻi, hiki ke hoʻohana ʻia ka sesamol e hana i ka ʻai holoholona i ka nui, nā puaʻa a me ka pipi. Pale i ka hōʻemi o ka oxidative i loko o ka mālama i mālama ʻia, ke hoʻomau nei ia ma ke ʻano maikaʻi ʻole me ka hoʻopuka ʻana i nā mea pili i nā hopena olakino e pili ana i nā mea kūʻai.

Eia kekahi, loaʻa i ka noiʻi nā pālua pālua pālua a me ka hoʻohui me nā mea kū i ka anti-oxidation e like me ka sesame penol hiki ke hoʻopaʻa pono i ka hoʻololi ʻana i ka hoʻololi ʻana i ka waiho ʻana o ka turkey umauma iʻa lau a me ka lau i kuke ʻia, lipid peroxidation a me ka molekahi a ka hoʻolaʻa, a laila e hoʻokō ai i ka. hopena o ka mālama.

Hoʻopilikia i nā hopena anti-tumor

Ua hōʻike ʻia kahi hōʻike noiʻi i ka hiki i ka sesamol i ka pale ʻana i ka ulu ʻana o nā cell lukemia i loko o ke kanaka. Hāʻawi ka oxidant maoli i kēia pōmaikaʻi i kahi paʻa-hilinaʻi. He mea pōmaikaʻi, ʻaʻole e like me kekahi mau mea hou aku i ka anti-tumor compound, ʻaʻole i ka hopena sesamol i nā hopena maikaʻi loa i nā ʻili kanaka maʻamau.

Scavenging waihue

Hiki i nā ʻōhaka manuahi ke hoʻoulu i nā kūlana olakino inā ke kūpaʻa ʻole ko lākou kūkulu maʻamau a me ke kinaʻewaʻewa ʻana. Ma waho aʻe o kēia, hiki i ke ʻano hōʻemi ʻōpio ʻole ke wikiwiki i ka wā ʻōpiopio i loko o kahi kanaka.

Eia kekahi, hiki i ka sesamol ke pale i ka hanauna o nā kaila hydroxyl a me nā anion superoxide, a laila e hoʻopiʻi i ke kino ʻO ke ʻano kaumaha o ka maʻi oxidative a me nā hana o ke ate ke loaʻa kekahi hopena kānāwai.

Hoʻoulu i ka maʻi metabolic syndrome

Wahi a ka metabolic syndrome e pili ana i kahi pilikia olakino pathological e hopena ana i nā maʻi metabolic e like me Obesity, hyperinsulinemia, maʻi maʻi a me ka hyperlipidemia.

Hiki i ka Sesamol ke hoʻomaikaʻi i ka momona (nui loa ka hōʻuluʻulu ʻana i ke kino momona ma ke kino) e:

ʻO ka hōʻemi i ka hōʻike lipogenic gen

Hoʻoulu i ka huaʻōlelo lipolytic Ppara

Ke ʻoki ʻana i ka hōʻike o nā ʻano mana i kuleana no ka hanauna kolamu (Hmgcr a me Acat2)

E like me ka sesamin, hiki i ka sesamol ke hoʻomaikaʻi i ka hana o ka mitochondria i loko o ka ate a me ka kiko adipose, e pale ai i ka momona.

Pākuʻi kūʻē

ʻO ke aniani mākou e noho nei, he nui ka hopena o nā maʻi he nui, he hoʻomaikaʻi i nā ʻepekema a me nā loea. ʻO ka mea pōmaikaʻi, ma muli o kahi noiʻi na Nair GG et al e hoʻokumu i ka hopena anti-radiation i ka sesamol, ua ʻike nā mea noiʻi ua hāʻawi aku nei ka pūhui i ka DNA a me ka membrane pale kupaianaha mai ka radiation hihiu.

Kahi e kūʻai sesamol paule i l?

Inā makemake ʻoe i ka Sesamol raw powder, ʻoluʻolu e kōkua iā mākou e hoʻokaʻaʻike mai iā mākou, ʻO mākou ka mea hoʻonaʻauao ʻenehana Sesamol no nā makahiki he nui, hoʻolako mākou i nā huahana me nā kumu kūʻai, nā lawelawe kūʻai maikaʻi a me nā huahana kūpono.
Hoʻonohonoho mākou me ka hana maʻamau o nā kauoha e kūpono i kāu pono pono a me kā mākou manawa wikiwiki i ka kauoha e hōʻoiaʻiʻo ana e ʻoluʻolu ʻoe me kā mākou lawelawe. Loaʻa mākou i nā nīnau a me nā ʻike e kākoʻo i kāu ʻoihana.

sesamelOLā kalaa Reference

1. Sesamol Archive 2010-01-14 ma ka Wayback Machine ma Chemicalland21.com
2. ʻO Joo Yeon Kim, ʻo Dong Seong Choi a me Mun Yhung Jung "Nā hana Antiphoto-oxidative o Sesamol ma Methylene Blue- a me Chlorophyll-Sensitized Photo-oxidation of Oil" J. Agric. Food Chem., 51 (11), 3460 -3465, 2003.
3. Ohsawa, Toshiko. "Sesamol a me ka sesaminol e like me antioxidants." Ke Kula Hana Hou Hou (1991), 33 (6), 1-5.
4. Wynn, James P .; Kendrick, Andrew; Ratledge, Colin. "ʻO Sesamol ma ke ʻano o ka mea hoʻomehana i ka ulu a me ka lipid metabolism ma Mucor circinelloides ma o kāna hana i ka malic enzyme." Lipids (1997), 32 (6), 605-610.
5. "Ke nānā aku nei kahi mea kokoke i Ayurvedic Medicine." Hoʻopiʻi i ka lāʻau lapaʻau hou a me nā mea hou aku. Bethesda, Maryland: National Center no ka Hoʻohui ʻokoʻa a me nā Kahuli (NCCAM), nā National National Institutes of Health (NIH). 12 (4). Hōʻulu 2005
6. Li, Jie Jack (2004). Contemporary kala kala. Hoboken, NJ: Wamika. ISBN 978-0-471-21480-9.Kaia: Nā mea kūlohelohePhenol